Biphasic multicomponent pharmaceutical dosage forms containing substances able to modify the partitioning of drugs
US6495160B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 1, 1999 |
| Grant date | Dec 17, 2002 |
| Priority date | — |
| Expiry date | Oct 1, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a biphasic multicomponent pharmaceutical composition consisting of an oil phase and a water phase, comprising one or more lipophilic or oil carrier, one or more hydrophilic or aqueous carrier, one or more ionic or nonionic type surfactant, one or more cosurfactant, one or more active principle for pharmaceutical use, and a compound able to modify the partition of the active principle between said phases selected from the group consisting of N- methyl pyrrolidone (NMP), isopropyl alcohol, propylene glycol, ethoxy-di-glycol, &bgr;-cyclodextrin, hydroxypropyl &bgr;-cyclodextrin and dimethyl &bgr;-cyclodextrin. The invention also provides a method for making the composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.