Regulation of cytokine production in a hematopoietic cell
US6495331B1 · kind B1 · utility
24Cited by
1References
39Claims
0Family size
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Key dates
| Filing date | May 5, 1999 |
| Grant date | Dec 17, 2002 |
| Priority date | — |
| Expiry date | May 5, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method useful for regulating cytokine production by a hematopoietic cell by regulating an MEKK/JNKK-contingent signal transduction pathway in such a cell is disclosed. Methods of identifying compounds capable of specifically regulating an MEKK/JNKK-contingent signal transduction pathway in hematopoietic cells, a kit for identifying cytokine regulators, methods to treat diseases involving cytokine production, and cells useful in such methods are also set forth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.