Method for reducing inflammation and inducing an analgesic effect and compounds thereof
US6495514B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 21, 1998 |
| Grant date | Dec 17, 2002 |
| Priority date | — |
| Expiry date | Jan 21, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/195
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a method for reducing inflammation in a subject by administering to the subject an effective amount of the compound having the structure I or II: wherein, R1 is C1-C10 branched or straight chain alkyl, aryl, an amino acid, or a peptide; and R2 is hydrogen or lower C1-C5 branched or straight alkyl, or the salt or ester thereof, wherein the stereochemistry about the carbon-carbon double bond is trans. The invention further relates to a method of inducing an analgesic effect by administering to a subject an effective amount of the compound having the structure I or II. The invention further relates to a compound having the structure II, wherein, R1 is an N-acyl amino acid or peptide, or the salt or ester thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.