Method for importing biologically active molecules into cells
US6495518B1 · kind B1 · utility
30Cited by
5References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 29, 1999 |
| Grant date | Dec 17, 2002 |
| Priority date | — |
| Expiry date | Nov 29, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized for purposes such as peptide therapy, gene transfer, and antisense therapy to regulate and/or eradicate systemic inflammatory response syndromes such as endotoxic shock.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.