Condensed thienopyrimidines with phosphodiesterase-v inhibiting action

US6495557B1 · kind B1 · utility

Assignee

• MERCK PATENT GESELLSCHAFT MIT BESHRANK TER HAFTUNG · DE

Inventors

• Rochus Jonas · Darmstadt, DE
• Pierre Schelling · Mühltal, DE
• Franz-Werner Kluxen · Darmstadt, DE
• Maria Christadler · Darmstadt, DE

Key dates

• Filing date: Mar 23, 2001
• Grant date: Dec 17, 2002
• Expiry date: Mar 23, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Thienopyrimidines of the formula I and their physiologically acceptable salts,in whichR1, R2 and X have the meanings given in claim 1, inhibit phosphodiesterase V and can be employed for the treatment of illnesses of the cardiovascular system and for the treatment and/or therapy of impaired potency.