Patent · US Expired

Therapeutic uses of il-1 receptor antagonist

US6497870B1 · kind B1 · utility

4Cited by
1References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 22, 2000
Grant dateDec 24, 2002
Priority date
Expiry dateMay 22, 2020

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides novel therapeutic methods of administering an amount of IL-1Ra to treat IL-18 related disorders. Specifically, the method involves treating IL-18 related disorders such as liver injury, hepatis, hemophagocytic lymphohistiocytosis, multiple sclerosis, tumors, cytotoxicity resulting from antitumor therapy, or other autoimmune disorders with a therapeutically effective amount of IL-1ra, and optionally measuring IFN-&ggr; and IL-18 activity from human samples.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.