Therapeutic uses of il-1 receptor antagonist
US6497870B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 2000 |
| Grant date | Dec 24, 2002 |
| Priority date | — |
| Expiry date | May 22, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel therapeutic methods of administering an amount of IL-1Ra to treat IL-18 related disorders. Specifically, the method involves treating IL-18 related disorders such as liver injury, hepatis, hemophagocytic lymphohistiocytosis, multiple sclerosis, tumors, cytotoxicity resulting from antitumor therapy, or other autoimmune disorders with a therapeutically effective amount of IL-1ra, and optionally measuring IFN-&ggr; and IL-18 activity from human samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.