Monoclonal antibodies that recognize antigens associated with tumor metastasis
US6498014B1 · kind B1 · utility
1Cited by
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3Claims
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Key dates
| Filing date | Feb 8, 2000 |
| Grant date | Dec 24, 2002 |
| Priority date | — |
| Expiry date | Feb 8, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides tumor metastasis-inhibiting monoclonal antibodies, mAb 41-2, mAb 50-6 and mAb 1A-5. The antigen recognized by mAb 50-6 and mAb 1A-5 has been identified as the PETA-3 antigen. The antigen recognized by mAb 41-2 has been identified as a novel tumor metastasis-associated antigen. Compositions and methods are provided that are useful for treating and diagnosing metastatic tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.