Patent · US Expired

Methods of identifying agents that modulate the binding between MDC and an MDC receptor

US6498015B1 · kind B1 · utility

35Cited by
7References
45Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 26, 1997
Grant dateDec 24, 2002
Priority date
Expiry dateSep 26, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides purified and isolated polynucleotide sequences encoding a novel human macrophage-derived C-C chemokine designated Macrophage Derived Chemokine (MDC), and polypeptide analogs thereof. Also provided are materials and methods for the recombinant production of the chemokine, and purified and isolated chemokine protein, and polypeptide analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.