One-component tissue adhesive and a process for the production thereof

US6500427B1 · kind B1 · utility

Assignee

• Aventis Behring GmbH · DE

Inventors

• Norbert Heimburger
• Peter Fuhge · Lahntal, DE
• Hansjorg Ronneberger · Marburg, DE

Key dates

• Filing date: Oct 20, 1994
• Grant date: Dec 31, 2002
• Expiry date: Oct 20, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A description is given of a one-component tissue adhesive containing, in aqueous solution, fibrinogen, F XIII, a thrombin inhibitor, prothrombin factors, calcium ions and, where appropriate, a plasmin inhibitor and of a process for the production thereof.This adhesive can be reconstituted from a freeze-dried form with water. It can contain aLL active substances in pasteurized form and is then free of the risk of transmission of hepatitis and HTLV III.