Delivery of a sacrificial substrate to inhibit protease permeation into skin
US6500443B1 · kind B1 · utility
8Cited by
33References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 25, 2000 |
| Grant date | Dec 31, 2002 |
| Priority date | — |
| Expiry date | May 25, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/782
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a topical delivery system effective in depositing a thin, tenacious and substantially continuous coating of a sacrificial substrate on skin by an aqueous emulsion mediated dissolution of protein from a sheet material with subsequent transfer and deposition onto the skin. Coatings of sacrificial substrate on skin resist removal, thereby providing a protective barrier against chemically- and biochemically-induced skin damage. The treatment composition also provides a vehicle for administering an effective dose of an active agent to the skin surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.