Inhibitors of bacterial NAD synthetase

US6500852B1 · kind B1 · utility

Assignee

• The University of Alabama Research Foundation · US

Inventors

• Wayne J. Brouillette · Pelham, US
• Donald D. Muccio · Hoover, US
• Mark J. Jedrzejas · Pelham, US
• Christie G. Brouillette · Pelham, US
• Yancho Devedjiev · Charlottesville, US
• Walter Cristofoli · Birmingham, US
• Lawrence J. DeLucas · Birmingham, US
• Jose Gabriel Garcia · Munich, DE
• Laurent Schmitt · Igny, FR
• Sadanandan E. Velu · Birmingham, US

Key dates

• Filing date: Jul 14, 2000
• Grant date: Dec 31, 2002
• Expiry date: Jul 14, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B40/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides methods of synthesizing and screening inhibitors of bacterial NAD synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial NAD synthetase enzyme.