Method for the catalytic production of substituted bipyridyl derivatives

US6500956B1 · kind B1 · utility

Assignee

• Axiva GmbH · DE

Inventors

• Holger Geissler · Mainz, DE
• Peter Gross · Saarlouis, DE

Key dates

• Filing date: Nov 30, 2000
• Grant date: Dec 31, 2002
• Expiry date: Nov 30, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/803
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the preparation of bipyridyls by converting at least one pyridine of the formula (III) in whichS′, S″, S′″, S″″ and S′″″, independently of one another, are identical or different and are hydrogen, (C1-C18)-alkyl, alkoxy-(C1-C18), acyloxy-(C1-C18), aryloxy-(C1-C18), perfluoroacyloxy-(C1-C8), NO2, (C1-C18)-aryl, (C1-C18)-heteroaryl, halogen, hydroxyl, nitro, nitroso, CN, COOH, CHO, PO3H2, SO3H, SO2R, SOR, NH2, NH-alkyl-(C1-C18), N-alkyl2-(C1-C18), protected amine, CF3, NHCO-alkyl-(C1-C4), N-alkyl-(C1-C4)-CO-alkyl-(C1-C4), COO-alkyl-(C1-C18), CONH2, CO-alkyl-(C1-C18), NHCOH, NHCOO-alkyl-(C1-C4), CO-(C1-C18)-aryl, COO-(C1-C18)-aryl, CHCH-CO2-alkyl-(C1-C18), CHCHCO2H, PO-phenyl2, PO-alkyl2-(C1-C4), (COO−)n(cation)n+, (PO32−)n(cation)2n+, (SO3−)n(cation)n+ and/or (O−)n(cation)n+,where optionally S′, S″, S′″, S″″ and/or S′″″ among one another together form one or more aliphatic and/or aromatic ringsand/or in which optionally S′, S″, S′″, S″″and/or S′″″forms a bridge t…