Transgentic mouse expressing green fluorescent protein in glial cells
US6501003B1 · kind B1 · utility
3Cited by
5References
3Claims
0Family size
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Key dates
| Filing date | Jul 8, 1998 |
| Grant date | Dec 31, 2002 |
| Priority date | — |
| Expiry date | Jul 8, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A transgenic mammal, specifically a mouse, containing in its genome a humanized mutant of green fluorescent protein operably linked to the glial fibrillary acidic protein promoter is provided. The mouse can be used to assay the effects of systemic or topical administration of neurotoxins and also to assay the effects of physical damage to neural tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.