Derivatives of choline binding proteins for vaccines
US6503511B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1999 |
| Grant date | Jan 7, 2003 |
| Priority date | — |
| Expiry date | Apr 6, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides bacterial immunogenic agents for administration to humans and non-human animals to stimulate an immune response. It particularly relates to the vaccination of mammalian species with pneumococcal derived polypeptides that include an alpha helix but exclude a choline binding region as a mechanism for stimulating production of antibodies that protect the vaccine recipient against infection by pathogenic bacterial species. In another aspect the invention provides antibodies against such proteins and protein complexes that may be used as diagnositics and/or as protective/treatment agents for pathogenic bacterial species.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.