Cytochrome b5 gene and protein of Candida tropicalis and methods relating thereto
US6503734B1 · kind B1 · utility
8Cited by
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22Claims
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Key dates
| Filing date | Jul 24, 2001 |
| Grant date | Jan 7, 2003 |
| Priority date | — |
| Expiry date | Jul 24, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel gene has been isolated which encodes cytochrome b5 (CYTb5) protein of the &ohgr;-hydroxylase complex of C. tropicalis 20336. Vectors including this gene, and transformed host cells are provided. Methods of increasing the production of a CYTb5 protein are also provided which involve transforming a host cell with a gene encoding this protein and culturing the cells. Methods of increasing the production of a dicarboxylic acid are also provided which involve increasing in the host cell the number of genes encoding this protein.
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