Patent · US Expired

Thienopyrimidine-based inhibitors of the Src family

US6503914B1 · kind B1 · utility

37Cited by
4References
99Claims
0Family size

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Inventors

Key dates

Filing dateOct 23, 2000
Grant dateJan 7, 2003
Priority date
Expiry dateOct 23, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Various thienopyrimidine-based analog compounds that selectively inhibit the Src family of tyrosine kinases. These compounds are thienopyrimidines and contain a hydrozone bridge created by heating a thienopyrimidine hydrazine with an aldehyde in ethanol at reflux. Such compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.