Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer
US6504149B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 28, 1999 |
| Grant date | Jan 7, 2003 |
| Priority date | — |
| Expiry date | May 28, 2019 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/044
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
This invention provides an apparatus and method for desolvating and selectively transmitting and focussing ions, including ions produced by electrospray ionization (ESI), based on the ion focussing principles of high field asymmetric waveform ion mobility spectrometry (FAIMS), for introduction into a mass spectrometer. The ion focussing, trapping and desolvating effects of FAIMS, as identified by the inventors, provides high ion transmission efficiency and high sensitivity for the detection of ions. An apparatus comprising an ESI source, a FAIMS device and a mass spectrometer provides a way of desolvating and selectively transmitting highly solvated ions for introduction into a mass spectrometer for analysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.