Processed polypeptides with IL-16 activity, process for preparing the same and their use

US6506582B1 · kind B1 · utility

Assignee

• Bundesrepublik Deutschland vertreten durch den Bundesminister fur Gesundheit · DE

Inventors

• Reinhard Kurth · Neu-Isenburg, DE
• Michael Baier · Frankfurt, DE
• Norbert Bannert · Frankfurt, DE
• Albrecht Werner · Weinheim, DE
• Kurt Lang · Penzberg, DE

Key dates

• Filing date: Feb 25, 1999
• Grant date: Jan 14, 2003
• Expiry date: Feb 25, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A nucleic acid which can be used to express a polypeptide with interleukin-16 activity in a prokaryotic or eukaryotic host cell wherein the nucleic acid codes for a polypeptide with the amino acid sequence SEQ ID NO:2 or a SEQ ID NO:2 elongated N-terminally by an aspartic acid residue or a form shortened at the C-terminus by up to 8 amino acids, and is suitable for the production of an active IL-16 polypeptide.