Non-M non-O HIV strains, fragments and uses

US6509018B1 · kind B1 · utility

Assignee

• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR

Inventors

• Phillippe Mauclere · Bordeaux, FR
• Ibtissam Loussert-Ajaka · Sartrouville, FR
• Francois Simon · Paris, FR
• Sentob Saragosti · Billancourt, FR
• Francoise Barre-Sinoussi · Issy-les-Moulineaux, FR

Key dates

• Filing date: Aug 27, 1999
• Grant date: Jan 21, 2003
• Expiry date: Aug 27, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/975
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides peptides which are expressed by the env gene of a non-M, non-O HIV-1 virus, in particular a strain designated YBF30. The invention also provides fragments of the peptides that including the V3 loop region and their corresponding nucleotide sequences. The invention further provides kits including diagnostic reagents containing these molecules or immunogenic compositions containing these peptides, as well as methods for screening and typing non-M, non-O HIV-1 viruses and HIV-1 viruses expressing these peptide and/or nucleotide sequences.