Wettable microcapsules having hydrophobic polymer coated cores
US6509034B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 10, 2000 |
| Grant date | Jan 21, 2003 |
| Priority date | — |
| Expiry date | Oct 10, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5047
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention concerns wettable microcapsules ethylcellulose coated cores and to processes for their preparation; in particular, to microcapsules with ethylcellulose coats that are wettable so that they are suspendable in aqueous medium. The wettable microcapsules can be prepared by applying ethylcellulose onto drug containing core by phase separation from a solvent to provide microcapsules, optionally washing said microcapsules with a solvent in which said microcapsules are substantially insoluble and drying, (a) one or more surfactants is/are incorporated in the solvent at the phase separation step; and/or (b) one or more surfactants is/are incorporated in the solvent used to wash the microcapsules; and/or said microcapsules being coated with one or more surfactants optionally in the presence of a binder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.