Patent · US Expired

1,5-Diaryl substituted pyrazoles as p38 kinase inhibitors

US6509361B1 · kind B1 · utility

24Cited by
2References
57Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 12, 2001
Grant dateJan 21, 2003
Priority date
Expiry dateFeb 12, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention contemplates 1,5-diaryl-substituted pyrazole compounds that, inter alia, inhibit the activity of p38 MAP kinase. Also contemplated by the invention are processes for the preparation of the contemplated compounds and for the use of a contemplated compound in treating a mammalian host having a p38 kinase- or TNF-mediated disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.