Paclitaxel formulation
US6509370B1 · kind B1 · utility
17Cited by
6References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2002 |
| Grant date | Jan 21, 2003 |
| Priority date | — |
| Expiry date | Jul 9, 2022 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical formulation is provided for delivering paclitaxel in vivo comprising: water and micelles comprising paclitaxel and a pharmaceutically-acceptable, water-miscible solubilizer forming the micelles, the solubilizer selected from the group consisting of solubilizers having the general structuresR1COOR2, R1CONR2, and R1COR2,wherein R1 is a hydrophobic C3-C50 alkane, alkene or alkyne and R2 is a hydrophilic moiety. The solubilizer is selected such that it does not have a pKa less than about 6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.