Branched hydrazone linkers
US6512101B1 · kind B1 · utility
34Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 19, 1998 |
| Grant date | Jan 28, 2003 |
| Priority date | — |
| Expiry date | Aug 19, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/252
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Branched hydrazone linkers for linking a targeting ligand such as an antibody to a therapeutically active drug. The point of branching is at a polyvalent atom and the number of drugs increases by a factor of two for each generation of branching. A preferred drug is doxorubicin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.