Synthesis for 4,10-dinitro-2,6,8,12-tetraoxa-4,10-diazatetracyclo[5.5.0.05,903,11]-dodecane
US6512113B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 8, 2000 |
| Grant date | Jan 28, 2003 |
| Priority date | — |
| Expiry date | Jul 29, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC06B25/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing 4,10-dinitro-2,6,8,12-tetraoxa-4,10-diazatetracyclo[5.5.0.05,903,11]-dodecane involves reacting at least one hexa-substituted piperazine derivative with at least one nitrate source and optionally at least one strong acid and heating the mixture to a temperature sufficient to induce an exothermic initial stage of the between the hexa-substituted piperazine derivative and the nitrate source. The mixture is maintained at a temperature in a range of at least ambient to not more than about 80° C. during the exothermic initial stage and at least a portion of a subsequent non-exothermic intermediate stage of the reaction by cooling the mixture during at least a portion of the exothermic initial stage of the reaction so that the reaction proceeds in a controlled manner. The mixture is then cooled to a temperature sufficiently low to prevent commencement of an exothermic NOx autocatalytic stage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.