Bioadhesive hydrogels with functionalized degradable crosslinks
US6514535B2 · kind B2 · utility
64Cited by
7References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 21, 1999 |
| Grant date | Feb 4, 2003 |
| Priority date | — |
| Expiry date | May 21, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0024
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to A bioadhesive composition comprising two or more essentially excretable, essentially non-degradable polymer backbones, wherein the polymer backbones are crosslinked, said crosslink being degradable in a mammal, said cross-linked bioadhesive composition having an average bioadhesion factor showing bioadhesion equivalent to at least about 100 g s. The concept is to build a hydrogel that demonstrates bioadhesion to a mucosal surface that is crosslinked by a degradable linkage such as disulfide for use inside the body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.