Process for detecting the malignant transformation of human cells
US6514708B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jan 16, 2001 |
| Grant date | Feb 4, 2003 |
| Priority date | — |
| Expiry date | Jan 27, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for detecting malignant transformation of cells involves detecting the overexpression of the products of the &bgr;3, &bgr;5, &bgr;8 and &bgr;9 genes, which encode the hCG&bgr; subunit, relative to their expression in nonmalignant cells. A kit for diagnosing an hCG- or an hCG fragment-secreting cancer includes an assembly of polypeptides covering at least a part of the primary sequence of hCG. The use of a polypeptide corresponding to at least one portion of the primary sequence of hCG for producing a composition useful in hCG- or hCG fragment-secreting cancer immunotherapy is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.