Patent · US Expired

Agouti polynucleotide compositions and methods of use

US6514747B2 · kind B2 · utility

4Cited by
10References
51Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 12, 2001
Grant dateFeb 4, 2003
Priority date
Expiry dateMar 14, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2840/445
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.