Patent · US Expired

Expression vectors for producing modified proteins

US6514753B1 · kind B1 · utility

7Cited by
8References
13Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 8, 1999
Grant dateFeb 4, 2003
Priority date—
Expiry dateFeb 8, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/90
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Modified proteins, modified interferons &agr;'s and &bgr;'s, phosphorylated modified proteins and DNA sequences encoding the above, applications and uses thereof. Modified phosphorylated Hu-IFN-&agr;-like proteins are provided which carry an identifiable label such as a radio-label. Corresponding phosphorylatable Hu-IFN-&agr;-like proteins which contain a putative phosphorylation site. DNA sequences which encode a Hu-IFN-&agr;-like protein and contain a sequence encoding a putative phosphorylatable site. Appropriate expression vectors are used to transform compatible host cells of various microorganisms, such as E. coli. Numerous uses for the phosphorylated proteins are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.