Antiviral methods using human rhinovirus receptor (ICAM-1)
US6514936B1 · kind B1 · utility
7Cited by
50References
4Claims
0Family size
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Key dates
| Filing date | Sep 30, 1994 |
| Grant date | Feb 4, 2003 |
| Priority date | — |
| Expiry date | Sep 30, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for substantially inhibiting initiation or spread of infection by rhinovirus or Coxsackie A virus of host cells expressing the major human rhinovirus receptor (ICAM-1), comprising the step of contacting the virus with a soluble polypeptide comprising the HRV binding site in domains I and II of ICAM-1; which polypeptide is capable of binding to the virus and reducing infectivity thereof; the contact being under conditions which permit the virus to bind to the polypeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.