Patent · US Expired

Formulated nucleic acid compositions and methods of administering the same for gene therapy

US6514947B2 · kind B2 · utility

10Cited by
15References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 11, 1997
Grant dateFeb 4, 2003
Priority date
Expiry dateFeb 11, 2017

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compositions and methods for administering nucleic acid compositions in vitro to cells in culture or in vivo to an organism whereby the uptake of nucleic acids is enhanced are provided. Various compositions, including those incorporating protective, interactive, non-condensing compounds, are utilized to protect and administered nucleic acid formulation, thereby prolonging the localized bioavailability of the administered nucleic acid and enhancing expression from the nucleic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.