Patent · US Expired

CRF receptor antagonists and methods relating thereto

US6514982B1 · kind B1 · utility

9Cited by
5References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 12, 1999
Grant dateFeb 4, 2003
Priority date
Expiry dateNov 12, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, such as stroke. The CRF receptor antagonists of this invention have the following structure: including stereoisomers and pharmaceutically acceptable salts thereof, wherein n, m, A, B, C, R, R1, R2 and Ar are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.