Cores for technetium radiopharmaceuticals
US6515112B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Oct 15, 2001 |
| Grant date | Feb 4, 2003 |
| Priority date | — |
| Expiry date | Oct 15, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B59/004
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 99mTc complex which contains the moiety Tc═NR, Tc—N═NY or Tc(—N═NY)2, and as a synthetic organic ligand which confers biological target-seeking properties on the technetium complex,where: R is an aryl group, a substituted or unsubstituted alkyl group or the group —NR1R2;Y is an aryl group or a substituted or unsubstituted alkyl group;R1 and R2 are H, aryl groups or substituted or unsubstituted aliphatic or cyclic alkyl groups, and are the same or different provided that both are not hydrogen;where at least one of the R or Y groups comprises an aryl group which chelates the 99mTc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.