Inhibitors of the ICE/ced-3 family of cysteine proteases
US6515173B1 · kind B1 · utility
3Cited by
3References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 13, 2000 |
| Grant date | Feb 4, 2003 |
| Priority date | — |
| Expiry date | Jan 13, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention s directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds having the following structure: wherein A, B, R, R1, p and q are as defined herein. The invention s all directed to pharmaceutical compositions containing one or more of thee compound, as well as to the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that to undergo a transplantation procedure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.