Chiral diphenyldiphosphines and d-8 metal complexes thereof

US6515183B2 · kind B2 · utility

Assignee

• SOLVIAS AG · CH

Inventors

• Benoit Pugin · Münchenstein, CH
• Ivo Steiner · Luzern, CH
• Rhony Aufdenblatten · Visp, CH
• Antonio Togni · Bremgarten, CH

Key dates

• Filing date: Jul 6, 2001
• Grant date: Feb 4, 2003
• Expiry date: Jul 6, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/50
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Compounds of formula III, wherein R6 und R7 signify identical or different secondary phosphino; R8 is —CH2—OH, —CH2—NH2, —CH2—O—B—FU, —CH2—NH2—B—FU, or —O—B—FU; R9 has the same significance as R8 or is C1-C4-alkyl or C1-C4-alkoxy; or R8 and R9 together signify HOCH(CH2—O—)2, H2NCH—(CH2—O—)2, FU—B—OCH(CH2—O—)2 or FU-B-HNCH(CH2—O—)2; B is a bridging group; and FU is a functional group. The compounds may be bonded to inorganic or organic carriers. Their d-8 metal complexes are valuable catalysts for the enantioselective hydrogenation of prochiral organic compounds with carbon multiple bonds or carbon/hetero atom multiple bonds.