Self-calibrating optical imaging system
US6516209B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 6, 2001 |
| Grant date | Feb 4, 2003 |
| Priority date | — |
| Expiry date | Feb 6, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/3144
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention generally relates to optical imaging systems and methods for providing images of two-dimensional and/or three-dimensional distribution of properties of chromophores in various physiological media. More particularly, the present invention relates to optical imaging systems, optical probes thereof, and methods therefore utilizing self-calibration of their output signals. A typical self-calibrating optical imaging system includes at least one wave source, at least one wave detector, a signal analyzer, a signal processor, and an image processor. The signal analyzer receives, from the wave detector, an output signal representative of the distribution of the chromophores or their properties in target areas of the medium. The signal analyzer analyzes amplitudes of the output signal and selects multiple points of the output signal having substantially similar amplitudes. The signal processor calculates a baseline corresponding to a representative amplitude of the similar amplitudes and provides a self-calibrated output signal. The image processor constructs the images of the distribution of the chromophores or their properties from the self-calibrated first output sig…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.