Bioactive prostheses with immunosuppressive, antistenotic and antithrombotic properties

US6517858B1 · kind B1 · utility

Assignees

• COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES · FR
• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• Kerckhoff-Klinik Gesellschaft mit beschrankter Haftung · DE

Inventors

• Alain Le Moel · Chaville, FR
• Natacha Betz · Boulogne-Billancourt, FR
• Christophe Bureau · Suresnes, FR
• Guy Deniau · Auffargis, FR
• Charles Baquey · Saint-Médard-en-Jalles, FR
• Gérard Deleris · Bordeaux, FR
• Werner Haberbosch · Brüggen, DE

Key dates

• Filing date: May 16, 2001
• Grant date: Feb 11, 2003
• Expiry date: May 16, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2400/18
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The invention relates to a bioactive implant comprising a substrate coated with a polymer layer with reactive functions, and a bioactive substance fixed on the implant by means of said reactive functions to enable progressive release on the implant site.Such implants are useful in the field of cardiology for example to prevent restenosis resulting from the fitting of stents in the coronary arteries.