Microcapsules for administration of neuroactive agents
US6517859B1 · kind B1 · utility
27Cited by
7References
57Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 29, 1994 |
| Grant date | Feb 11, 2003 |
| Priority date | — |
| Expiry date | Jun 29, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient. Microspheres of less than 45 &mgr;m, preferably less than about 20 &mgr;m, and preferably about 0.1 &mgr;m to about 10 &mgr;m in mean diameter according to the present invention are also selectively taken-up and into astrocytes when delivered directly into the nervous tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.