Patent · US Expired

1H-imidazopyridine derivatives

US6518265B1 · kind B1 · utility

181Cited by
5References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 2, 2001
Grant dateFeb 11, 2003
Priority date
Expiry dateMay 2, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

1H-Imidazopyridine derivatives represented by the following general formula or salts thereof: wherein R1 represents hydrogen atom, hydroxyl group, an alkyl group, a cycloalkyl group, styryl group, or an aryl group; R2 represents hydrogen atom, an alkyl group, a halogen atom, hydroxyl group, amino group, a cyclic amino group, or phenoxy group; ring A represents a homocyclic or heterocyclic ring which may be substituted; R3 represents a saturated nitrogen-containing heterocyclic group; and m represents an integer of from 0 to 3. The derivatives have excellent inhibitory actions against production of TNF or IL-1 and are extremely useful as preventive or therapeutic agents for diseases in which a cytokine is mediated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.