1- Aryl-3-thioalkyl pyrazoles, the synthesis thereof and the use thereof as insecticides

US6518266B1 · kind B1 · utility

Assignees

• 3-Dimensional Pharmaceuticals, Inc. · US
• Heska Corporation · US

Inventors

• Daljit S. Dhanoa · Wakefield, US
• Dario Doller · Wallingford, US
• Sanath K. Meegalla · Boothwyn, US
• Richard Soll · San Diego, US
• Nancy Wisnewski · Fort Collins, US
• Gary M. Silver · Fort Collins, US
• Dan T. Stinchcomb · Boulder, US
• R. Lee Seward · Eaton, US
• Dimitris Agrafiotis · Downingtown, US
• Deyou Sha · Yardley, US

Key dates

• Filing date: Jul 21, 2000
• Grant date: Feb 11, 2003
• Expiry date: Jul 21, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention is directed to novel pyrazole derivatives and their use as pesticidal agents. The pyrazole derivatives have Formula I: or a salt thereof, whereR1 represents R5O, R5SO2, R5SO or R5S in which R5 is as defined herein;X is halo, cyano, C1-6 alkoxycarbonyl, C2-6 alkynyl, optionally substituted C6-14 aryl or an optionally substituted 5- to 7-membered heteroaromatic ring linked to thiazole via a carbon-carbon bond;R2 is hydrogen, amino, chloro, bromo, iodo, cyano, C1-6 alkoxy, C1-6 alkyl or C6-10 aryl; andR3-R7 each represent hydrogen, halogen, straight- or branched-chain C1-4 alkyl or C1-4 alkoxy, either of which is unsubstituted or substituted by one or more halogen atoms, straight- or branched-chain C1-4 alkylthio or C1-4 alkylsulphinyl, either of which is substituted by one or more halogen atoms, nitro, cyano, or straight- or branched-chain C1-4 alkylsulphonyl group which is unsubstituted or substituted by one or more halogen atoms.