Telomerase inhibitors and methods of their use
US6518268B1 · kind B1 · utility
33Cited by
38References
33Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 30, 2000 |
| Grant date | Feb 11, 2003 |
| Priority date | — |
| Expiry date | Jun 30, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Thiazolidinedione compounds, compositions, and methods of inhibiting telomerase activity in vitro and treatment of telomerase mediated conditions or diseases ex vivo and in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination with other pharmacologically active agents in the treatment of conditions or diseases mediated by telomerase activity, such as in the treatment of cancer. Also disclosed are novel methods for assaying or screening for inhibitors of telomerase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.