Heterocyclic aromatic compounds usefuls as growth hormone secretagogues
US6518292B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 18, 2000 |
| Grant date | Feb 11, 2003 |
| Priority date | — |
| Expiry date | Feb 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Heterocyclic aromatic compounds are provided which are useful in stimulating endogenous production or release of growth hormone and in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.The heterocyclic aromatic compounds have the structure including pharmaceutically acceptable salts thereof and all stereoisomers thereof,wherein Xa is heteroaryl, preferably,  and R1, R1a, R6, Y, Xb, A, B, Z, R3, R4, R4a, R5 and R5a are as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.