Process for selective oxidation of primary alcohols
US6518419B1 · kind B1 · utility
55Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 7, 2000 |
| Grant date | Feb 11, 2003 |
| Priority date | — |
| Expiry date | Mar 7, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B31/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Primary alcohols, especially in carbohydrates, can be selectively oxidized to aldehydes and carboxylic acids in a low-halogen process by using a peracid in the presence of a catalytic amount of a di-tertiary-alkyl nitroxyl (TEMPO) and a catalytic amount of halide. The halide is preferably bromide and the process can be carried out at nearly neutral to moderately alkaline pH (5-11). The peracid can be produced or regenerated by means of hydrogen peroxide or oxygen. The process is advantageous for producing uronic acids and for introducing aldehyde groups which are suitable for crosslinking and derivatization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.