Precipitation process of 7-aminocephalosporanic acid (7-ACA)

US6518420B2 · kind B2 · utility

Assignee

• Biochemie Gesellschaft m.b.H · AT

Inventors

• Petr Nadenik · Kufstein, AT
• Helmut Wagner · Duderstadt, DE

Key dates

• Filing date: Nov 7, 2001
• Grant date: Feb 11, 2003
• Expiry date: Nov 7, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D501/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process in the isolation of 7-aminocephalosporanic acid (7-ACA) from an alkaline, neutral or slightly acidic medium in the presence of an additive, e.g. selected from the group comprising organic carboxylic acid esters, polymeric glycols, polyacryls, amines and polyamines, melaminformaldehyde resins or amino acids and esters thereof to obtain 7-ACA agglomerates and or rosettes.