Method of manufacture of 1,3-oxathiolane nucleosides
US6518425B1 · kind B1 · utility
2Cited by
27References
18Claims
0Family size
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Key dates
| Filing date | May 15, 2000 |
| Grant date | Feb 11, 2003 |
| Priority date | — |
| Expiry date | May 15, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D411/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.