Patent · US Expired

Mutant of tissue factor pathway inhibitor, DNA sequence and use for detecting thrombotic disorders

US6521410B1 · kind B1 · utility

0Cited by

0References

11Claims

0Family size

Assignee

Knut Kleesiek · DE

Inventors

Thomas Brinkmann · Bielefeld, DE
Wolfgang Prohaska · Oeynhausen, DE
Christian Goetting · Diepholz, DE
Michael March Schmidt · Cambridge, US

Key dates

Filing date	Jun 9, 2001
Grant date	Feb 18, 2003
Priority date	—
Expiry date	Jun 9, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/8114
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to a novel mutant of tissue factor pathway inhibitor (TFPI) protein and its corresponding DNA sequence. The mutant can be found in humans who show or may show an increased risk of thrombotic diseases. By screening samples of human blood for said DNA or fragments of it, it is possible to predict a disposition of thrombotic disorders by which prophylactic application or measures can be initiated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.