Patent · US Expired

3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors

US6521618B2 · kind B2 · utility

59Cited by
10References
136Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 28, 2001
Grant dateFeb 18, 2003
Priority date
Expiry dateMar 28, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.