Quinoline and quinazoline compounds useful in therapy
US6521629B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 13, 2001 |
| Grant date | Feb 18, 2003 |
| Priority date | — |
| Expiry date | Nov 13, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I, whereinR1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms;R2 represents H or C1-4 alkoxy optionally substituted by one or more fluorine atoms;R3 represents a 5- or 6-membered heterocyclic ring, the ring being optionally substituted;R4 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent, or represents a cyclic group of formula Ia,  or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof; are useful in therapy, in particular in the treatment of benign prostatic hyperplasia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.