Use of ligands for treatment of diseases responsive to retinoids
US6521814B1 · kind B1 · utility
1Cited by
3References
73Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 22, 1998 |
| Grant date | Feb 18, 2003 |
| Priority date | — |
| Expiry date | Dec 22, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to methods for treatment of neurological disease by administering an agent which interacts with a retinoid receptor associated with the neurological disease. The invention is also related to a method of modulating dopamine receptor synthesis by introducing an agent that interacts with a retinoid receptor associated with the dopamine receptor synthesis. The invention is further related to a transgenic animal, e.g., mouse, and mammalian cell line, which is deficient in the normal synthesis of one or more receptors of RAR&agr;, &bgr;, &ggr; and RXR, and cell line thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.