Patent · US Expired

Expression cloning processes for the discovery, characterization and isolation of genes encoding polypeptides with a predetermined property

US6524792B1 · kind B1 · utility

16Cited by
13References
63Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 17, 1998
Grant dateFeb 25, 2003
Priority date
Expiry dateNov 17, 2018

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/912
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention is directed to a method for detection, characterization and isolation of nucleic acids encoding proteins of a desired property, such as a particular cellular localization. The invention further provides for rapid expression of such proteins or glycoproteins in mammalian cells and for facilitated purification of the novel secreted proteins or glycoproteins. Further, the invention provides for radioactive labelling of the novel proteins or glycoproteins, for rapid identification of sites of binding including animals and for rapid production of infective viral vectors for use in gene transfer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.