Patent · US Expired

Multiplexed analysis of clinical specimens apparatus and method

US6524793B1 · kind B1 · utility

205Cited by
79References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 18, 1999
Grant dateFeb 25, 2003
Priority date
Expiry dateJun 18, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/973
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.